iTOL-201

Developing a Potential Treatment for Liver Failure

Current approaches to liver implantation require life-long immunosuppression. The advent of expanding liver cells (known as hepatocytes) to treat liver failure using donated liver organs or stem cell-derived organoids, which function like liver cells would be greatly enhanced if both donated livers and/or life-long immunosuppression could be eliminated. iTOL-201 is a combination of iTOL-100 together with hepatocytes to potentially treat liver failure without the need for life-long immunosuppression.